NIPER-JEE - 2024

NIPER-JEE - National Institute of Pharmaceutical Education and Research Joint Entrance Examination

NIPER JEE 2024 refers to the National Institute of Pharmaceutical Education and Research Joint Entrance Examination scheduled to take place in 2024. It is an entrance exam conducted for admissions into postgraduate courses in pharmacy and related fields at NIPER institutes across India.
Eligibility

   Candidates must have completed a Bachelor's degree in Pharmacy (B. Pharm), Pharmaceutical Sciences, or Medicine (MBBS) from a recognized university or institute. The minimum qualifying percentage may vary, but it is typically around 60% or 6.75 CGPA.

Syllabus

Natural Products

Secondary metabolites

Phytochemistry

Methods of extraction, isolation, and characterization of natural products

Biosynthetic pathways

Important therapeutic classes

Primary metabolites

Marine natural products

Plant growth regulators

Spectroscopy

Dietary antioxidants

 

 
Stereochemistry

Pharmacology and toxicology

Evaluation of formulation, principles, and methods of release control in oral formulations

Bioavailability, bioequivalence studies

Compartmental modelling

Packaging

Dosage forms

Additives of formulation, types, examples, advantages, disadvantages, drug excipient interaction, incompatibility, various types of incompatibilities

(TDDS)

 Fischer, sawhorse and Newman projection formulas

 Standardization of natural products

 Various adrenergic, cholinergic and other receptors

 Pharmaceutics and formulation (Pharmaceutical Technology)

 Pharmacokinetics

 Pharmacodynamics

 The pharmacological effect, desired, undesired, toxic, adverse effects

 Bioavailability, bioequivalence, various factors of ADME

 Drug metabolism

 Drug interactions, agonist, antagonist, protein binding, drug distribution, distribution volume, excretion pathways

 Pharmacological screening

 Mechanism of drug action

 Drug-receptor interaction

 Detailed study of CNS pharmacology Transdermal drug delivery systems

 Diseases

 Chemotherapy and pathophysiology

 Bioassay methods

 Drug delivery systems (DDS)

 Carriers in DDS

 Biological sources of important classes of natural products

 Parenteral

 Drug targeting

Complexation

Solubilisation

Dosage form development- stages, implications of dosage form

Viscosity measurements

 

Pharmaceutical analysis

Stability testing of pharmaceuticals, various stability tests, kinetic studies, shelf-life determination, thermal stability, formulation stability

Various analytical techniques

Tests: physical and chemical tests, limit tests, microbiological tests, biological tests, disintegration and dissolution tests.

Solubility

Transdermal drug delivery systems (TDDS): principles, absorption enhancers, evaluation of TDDS.

Carriers in DDS: polymers and their classification, types, carbohydrates, surfactants, proteins, lipids, prodrugs etc. 

Drug delivery systems (DDS): NDDS models, osmotic pumps, various release patterns

Osmolality, osmolality, osmotic pressure, conductivity, Preservatives, Media for bioassay.

Spectroscopic methods

Electrophoresis

UV-Visible

NMR

XRD

IR

Fluorimetry

 HPLC

 IR

 GC

 LCMS

 Mass

 NMR Peaks

 Particle sizing

 Chromatography- detailed QA and QC: GLP, TQM, ISO system

 Preformulation, cyclodextrin inclusion compounds

 Crystallinity, polymorphism, solvates and hydrates, crystal habits, porosity, surface area flow properties.

 Dosage forms, Stages of dosage form development

 

Biotechnology and biochemistry

Pharmaceutical technology

Classification of enzymes and the mechanism of their function of action of

 Genetic Engineering

 Blotting techniques(Western, southern)

 Gel electrophoresis

 Gene cloning

 Immunoassays, protein

 RNA synthesis

 DNA synthesis

 DNA technology

Gene expression

Mutation

Replication

Transcription, translation

Recombination, bacteriophages

Cloning

Fermentation

Methods, isolation of nucleic acids, enzymes in cloning

 

Chemistry

Basic organic chemistry and biochemistry Stereochemistry

Osazone test

Mutarotation

Medicinal chemistry and Bulk Drugs

Keto-enol tautomerism

IUPAC nomenclature

Introduction to thermal methods of analysis

Introduction to Redox reactions

Imine-enamine

Hybridization

Amino acids proteins

Type of stereoisomer

Basic methods of synthesis of various organic compounds

Named reactions

Various Heterocycles, Heterocycle synthesis, reactions

Tautomerism

Spectroscopy

Resolution methods

Reaction kinetics, first second third and pseudo-first-order reactions, radiolabeling for determination of mechanism.

Racemic mixture

R and S nomenclature

Reactions like Cannizarro’s reaction

Pericyclic reactions

Ester hydrolysis

Huckel’s rule reaction mechanisms-

E and Z isomerism

Common condensation reactions like Aldol, Claisen Perkin, Dickmann, Darzen

Chromatography

Carbohydrates classification

Aromaticity

 

Aptitude

Simple Mathematics

logical reasoning and data analysis,

questions based on the English language 

 

 

Pharmacology

Bioavailability, bioequivalence, various factors of ADME

Bioassay methods, various requirements. Brief knowledge of the statistical tests.

Chemotherapy and pathophysiology- knowledge of antibiotics, their mode of action and the microorganisms responsible for various common diseases.

Diseases: a study of the pharmacology of the diseases and drugs used with the mode of action especially of diabetes, malaria, leishmaniasis, TB, hypertension, myocardial ischemia, inflammation, and immunomodulation.

Study of the basis of threshold areas of work in NIPER in the pharmacology dept. Mentioned in the brochure.

Detailed study of CNS pharmacology especially opioid receptors

Pharmacokinetics, pharmacodynamics, pharmacological effect, desired, undesired, toxic, adverse effects.

Drug metabolism: various pathways and other details.

Drug interactions, agonist, antagonist, Mechanism of drug action, drug-receptor interaction.

Various adrenergic, cholinergic and other receptors

Partial agonist, protein binding, drug distribution, distribution volume, excretion pathways etc.

 

Phytochemistry

Methods of extraction, isolation, and characterization of natural products.

Various separation techniques used for the isolation of natural products.

Biosynthetic pathways.

Primary metabolites, their examples

Secondary metabolites, various classes of secondary metabolites (Alkaloids, glycosides, tannins, lignans, saponins, lipids, flavonoids, coumarins, etc.).

Important therapeutic classes: anti-diabetics, hepato-protectives, immunomodulators, nutraceuticals, natural products for gynaecological disorders, anti-cancer, anti-viral (mainly anti-HIV), adaptogens etc.

Dietary antioxidants, Marine natural products, plant growth regulators.

Fischer projection formulas.

Biological sources of important classes of natural products. (Selected ones only)

Standardization of natural products, analytical pharmacognosy.

Difference between natural products and pharmacognosy

Some knowledge about types and preparation of ayurvedic formulations like asava, arista etc.


Exam Date

Exam dates (Tentative)             Events

April 2024 - May 2024                 NIPER JEE 2024 application form release date

June 2024 - July 2024                  NIPER JEE 2024 Admit Card release date

July 2024                                      NIPER JEE Exam Date

July 2024                                      NIPER JEE 2024 Result Announcement date

 

Official site- https://niperguwahati.ac.in/

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